Halcyon Molecular was developing a system based on electron microscopy. The system was intended to work by stretching out very long individual molecules of DNA (up to 150kb) and staining them with contrast agents, allowing for the determination of individual bases with an electron microscope. When founded in 2009, the company claimed to be aiming for a system which could sequence human genomes for $100 in 10 minutes. However, it appears that they felt they wouldn’t be able to keep up with other cutting edge technologies, as they made the decision to shut down in mid-2012.
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