Reveo is creating a next-gen sequencer based on atomic force microscopy via their ReVase subsidiary. The system, called the Omni Molecular Recognizer Application (OmniMoRA), will use arrays of nano-knife edge probes to measure the vibrational characteristics of individual bases on DNA molecules that have been stretched and immobilized on a surface. While Reveo has not […]
The latest developments in the next ‘next generation’ sequencing platforms that are promising to dethrone the current market entrants.
Stratos Genomics is building a nanopore-based single molecule sequencer. However, rather than directly sequencing the native DNA molecule, they have developed a process they call ‘sequencing-by-expansion’. They convert the DNA into an expanded molecule, or ‘xpandomer’, through a process similar to replication via polymerase. However, rather than incorporating a single base at a time into […]
Two Pore Guys is an early stage technology development company that is attempting to address the issue of DNA flow rate through nanopores. Instead of reading strands of DNA through a single pore, they are using two pores in series such that the DNA molecule is held by both. By applying opposing currents through the […]