Status: merged and acquired Lynx developed their MPSS (“massively parallel signature sequencing”) technology for generating tag-based RNA sequencing data. They were acquired by Solexa in 2005 via a reverse merger (Lynx was a public company and took the Solexa name and management). The combined company was acquired by Illumina in 2006. Please contact us at […]
Sequencing companies are born and sequencing companies die. Or get acquired. Or just change their names. We honor those that have come before us.
Status: ceased operations; technology acquired Manteia developed the initial ‘bridge amplification’ technology that is currently used by Illumina sequencers. They were shut down in 2003 by their owners, Serono, and the technology was sold to Solexa (and Lynx) in 2004 to help them make their move away from single molecule sequencing. Please contact us at […]
Status: name change Nanofluidics changed their name to Pacific Biosciences in 2005. Please contact us at firstname.lastname@example.org if you have any information or opinions you’d like to share about this page.
Status: technology licensed off Pyrosequencing AB developed the sequencing chemistry from which it took its name. In 2003 they acquired Biotage and changed their name to that of the acquired company. Biotage was later sold to Qiagen who has licensed the pyrosequencing technology exclusively to 454 (now Roche) for high density/high throughput sequencing applications. Please […]
Status: no longer developing NGS platform Sequenom acquired IP relating to NGS from Harvard University (based on Amit Meller’s work) in 2007 with the aim of developing their own NGS-based diagnostic platform. In 2010 they returned the technology to Harvard. While Sequenom is using NGS technology in developing their diagnostic products, they no longer appear […]
Status: acquired Solexa developed a sequencer based on sequencing-by-synthesis and bridge amplification technology. In 2006, prior to full commercialization of the new system, they were acquired by Illumina. The Solexa technology forms the basis for all of Illumina’s sequencing systems to date. Please contact us at email@example.com if you have any information or opinions you’d […]
Life Technologies’ (now ThermoFisher) SOLiD sequencing platform uses emulsion PCR (emPCR) and a sequencing-by-ligation approach that generates results in “color space.” While they haven’t officially discontinued the platform, they are no longer actively promoting it and don’t appear to be developing it or selling new instruments. The information below was last updated in […]
Status: ceased operations; technology acquired and shelved VisiGen was developing a single molecule sequencer when they were acquired by Life Technologies (Invitrogen) in 2008 for $20M. The technology, now known by the codename ‘Starlight’, has been deprioritized due to the focus on the SOLiD and Ion Torrent technologies. In a recent court filing in the […]
Status: ceased operations Xagros Genomics was formed in 2001 based on IP for charge detection during DNA synthesis from Ron Davis’ lab at Stanford. After the company folded in 2004, the IP reverted back to Stanford and was later acquired by Ion Torrent.
ZS Genetics was acquired by Genetics Research, and no longer appears to be operating or developing a sequencing platform. They were developing a single molecule sequencer based on annular dark-field scanning transmission electron microscopy (ADF-STEM). Since native DNA is invisible to the STEM imager, their strategy was to incorporate ‘ZSG labels’, modified nucleotides with heavy atoms […]